Abstract
Although the biokinetics of polonium has been studied extensively, interpretation of the data is complicated by potential differences with species and route of exposure and the questionable reliability of much of the reported excretion data for man. A study was undertaken to identify the data that are most likely to represent the typical behavior of polonium and apply those data to construct an improved, physiologically realistic systemic biokinetic model for polonium in man. Such a model is needed for interpretation of urinary excretion data for workers exposed to 210Po and reconstruction of the radiation doses received by those workers. This paper reviews the database on the biokinetics of polonium and describes a new systemic biokinetic model for polonium in man.
| Original language | English |
|---|---|
| Pages (from-to) | 109-125 |
| Number of pages | 17 |
| Journal | Science of the Total Environment |
| Volume | 275 |
| Issue number | 1-3 |
| DOIs | |
| State | Published - Jul 25 2001 |
Funding
This work was sponsored by MJW Corporation, Inc., under DOE/WFO Project Number ERD9801684, under contract DE-AC05-84OR21400 with Lockheed Martin Energy Research Corporation. The authors are grateful to David A. Dooley of MJW Corporation, Inc., for his support and encouragement; to Alan Fellman and Lowell Ralston for helpful discussions of their excellent studies of the behavior of polonium in non-human primates and the potential limitations of older techniques for measuring 210 Po in urine; and to Joseph Moon for providing laboratory reports and useful background information on the measurement of 210 Po in workers.
| Funders | Funder number |
|---|---|
| Lockheed Martin Energy Research Corporation | |
| MJW Corporation, Inc. | |
| WFO | ERD9801684, DE-AC05-84OR21400 |
| U.S. Department of Energy |
Keywords
- Database
- Polonium
- Systemic biokinetic model
- Urinary excretion