A suite-level review of the neutron single-crystal diffraction instruments at Oak Ridge National Laboratory

L. Coates; H. B. Cao; B. C. Chakoumakos; M. D. Frontzek; C. Hoffmann; A. Y. Kovalevsky; Y. Liu; F. Meilleur; A. M. Dos Santos; D. A.A. Myles; X. P. Wang; F. Ye

doi:10.1063/1.5030896

A suite-level review of the neutron single-crystal diffraction instruments at Oak Ridge National Laboratory

L. Coates, H. B. Cao, B. C. Chakoumakos, M. D. Frontzek, C. Hoffmann, A. Y. Kovalevsky, Y. Liu, F. Meilleur, A. M. Dos Santos, D. A.A. Myles, X. P. Wang, F. Ye

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Abstract

The nascent suite of single-crystal neutron diffractometers at the Oak Ridge National Laboratory has no equal at any other neutron scattering facility worldwide and offers the potential to re-assert single-crystal diffraction using neutrons as a significant tool to study nuclear and magnetic structures of small unit cell crystals, nuclear structures of macromolecules, and diffuse scattering. Signature applications and features of single-crystal neutron diffraction are high resolution nuclear structure analysis, magnetic structure and spin density determinations, contrast variation (particularly D₂O/H₂O) for nuclear structural studies, lack of radiation damage when using crystals of biological molecules such as proteins, and the fidelity to measure nuclear and magnetic diffuse scattering with elastic discrimination.

Original language	English
Article number	092802
Journal	Review of Scientific Instruments
Volume	89
Issue number	9
DOIs	https://doi.org/10.1063/1.5030896
State	Published - Sep 1 2018

Funding

Research at ORNL’s HFIR and Spallation Neutron Source was sponsored by the Scientific User Facilities Division, Office of Basic Energy Sciences, U.S. Department of Energy. The Office of Biological and Environmental Research supported research at Oak Ridge National Laboratory’s Center for Structural Molecular Biology (CSMB), using facilities supported by the Scientific User Facilities Division, Office of Basic Energy Sciences, U.S. Department of Energy. Research at ORNL's HFIR and Spallation Neutron Source was sponsored by the Scientific User Facilities Division, Office of Basic Energy Sciences, U.S. Department of Energy. The Office of Biological and Environmental Research supported research at Oak Ridge National Laboratory's Center for Structural Molecular Biology (CSMB), using facilities supported by the Scientific User Facilities Division, Office of Basic Energy Sciences, U.S. Department of Energy.

Funders	Funder number
Oak Ridge National Laboratory
Office of Basic Energy Sciences
Scientific User Facilities Division
U.S. Department of Energy
Basic Energy Sciences
Oak Ridge National Laboratory
Canadian Society for Molecular Biosciences

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Coates, L., Cao, H. B., Chakoumakos, B. C., Frontzek, M. D., Hoffmann, C., Kovalevsky, A. Y., Liu, Y., Meilleur, F., Dos Santos, A. M., Myles, D. A. A., Wang, X. P., & Ye, F. (2018). A suite-level review of the neutron single-crystal diffraction instruments at Oak Ridge National Laboratory. Review of Scientific Instruments, 89(9), Article 092802. https://doi.org/10.1063/1.5030896

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A suite-level review of the neutron single-crystal diffraction instruments at Oak Ridge National Laboratory

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