Abstract
Scientific discovery is being revolutionized by AI and autonomous systems, yet current autonomous laboratories remain isolated islands unable to collaborate across institutions. We present the Autonomous Interconnected Science Lab Ecosystem (AISLE), a grassroots network transforming fragmented capabilities into a unified system that shorten the path from ideation to innovation to impact and accelerates discovery from decades to months. AISLE addresses five critical dimensions: (1) cross-institutional equipment orchestration, (2) intelligent data management with FAIR compliance, (3) AI-agent driven orchestration grounded in scientific principles, (4) interoperable agent communication interfaces, and (5) AI/ML-integrated scientific education. By connecting autonomous agents across institutional boundaries, autonomous science can unlock research spaces inaccessible to traditional approaches while democratizing cutting-edge technologies. This paradigm shift toward collaborative autonomous science promises breakthroughs in sustainable energy, materials development, and public health.
| Original language | English |
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| Title of host publication | 54th International Conference on Parallel Processing, ICPP 2025 - Workshops Proceedings |
| Publisher | Association for Computing Machinery, Inc |
| Pages | 142-150 |
| Number of pages | 9 |
| ISBN (Electronic) | 9798400721090 |
| DOIs | |
| State | Published - Dec 20 2025 |
| Event | 54th International Conference on Parallel Processing Workshop, ICPP 2025 - San Diego, United States Duration: Sep 8 2025 → Sep 11 2025 |
Publication series
| Name | 54th International Conference on Parallel Processing, ICPP 2025 - Workshops Proceedings |
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Conference
| Conference | 54th International Conference on Parallel Processing Workshop, ICPP 2025 |
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| Country/Territory | United States |
| City | San Diego |
| Period | 09/8/25 → 09/11/25 |
Funding
This research used resources of the Oak Ridge Leadership Computing Facility, and is sponsored by the INTERSECT Initiative as part of the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC05-00OR22725.
Keywords
- Autonomous Discovery
- Autonomous Science
- Labs of the Future
- Scientific Workflows