A Grassroots Network and Community Roadmap for Interconnected Autonomous Science Laboratories for Accelerated Discovery

  • Rafael Ferreira Da Silva
  • , Milad Abolhasani
  • , Dionysios A. Antonopoulos
  • , Laura Biven
  • , Ryan Coffee
  • , Ian T. Foster
  • , Leslie Hamilton
  • , Shantenu Jha
  • , Theresa Mayer
  • , Benjamin Mintz
  • , Robert G. Moore
  • , Salahudin Nimer
  • , Noah Paulson
  • , Woong Shin
  • , Frédéric Suter
  • , Mitra Taheri
  • , Michela Taufer
  • , Newell R. Washburn

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

Scientific discovery is being revolutionized by AI and autonomous systems, yet current autonomous laboratories remain isolated islands unable to collaborate across institutions. We present the Autonomous Interconnected Science Lab Ecosystem (AISLE), a grassroots network transforming fragmented capabilities into a unified system that shorten the path from ideation to innovation to impact and accelerates discovery from decades to months. AISLE addresses five critical dimensions: (1) cross-institutional equipment orchestration, (2) intelligent data management with FAIR compliance, (3) AI-agent driven orchestration grounded in scientific principles, (4) interoperable agent communication interfaces, and (5) AI/ML-integrated scientific education. By connecting autonomous agents across institutional boundaries, autonomous science can unlock research spaces inaccessible to traditional approaches while democratizing cutting-edge technologies. This paradigm shift toward collaborative autonomous science promises breakthroughs in sustainable energy, materials development, and public health.

Original languageEnglish
Title of host publication54th International Conference on Parallel Processing, ICPP 2025 - Workshops Proceedings
PublisherAssociation for Computing Machinery, Inc
Pages142-150
Number of pages9
ISBN (Electronic)9798400721090
DOIs
StatePublished - Dec 20 2025
Event54th International Conference on Parallel Processing Workshop, ICPP 2025 - San Diego, United States
Duration: Sep 8 2025Sep 11 2025

Publication series

Name54th International Conference on Parallel Processing, ICPP 2025 - Workshops Proceedings

Conference

Conference54th International Conference on Parallel Processing Workshop, ICPP 2025
Country/TerritoryUnited States
CitySan Diego
Period09/8/2509/11/25

Funding

This research used resources of the Oak Ridge Leadership Computing Facility, and is sponsored by the INTERSECT Initiative as part of the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC05-00OR22725.

Keywords

  • Autonomous Discovery
  • Autonomous Science
  • Labs of the Future
  • Scientific Workflows

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