A Glucose Biosensor Using CMOS Potentiostat and Vertically Aligned Carbon Nanofibers

Khandaker A. Al Mamun; Syed K. Islam; Dale K. Hensley; Nicole McFarlane

doi:10.1109/TBCAS.2016.2557787

A Glucose Biosensor Using CMOS Potentiostat and Vertically Aligned Carbon Nanofibers

Khandaker A. Al Mamun, Syed K. Islam, Dale K. Hensley, Nicole McFarlane

Nanofabrication Research Laboratory

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

This paper reports a linear, low power, and compact CMOS based potentiostat for vertically aligned carbon nanofibers (VACNF) based amperometric glucose sensors. The CMOS based potentiostat consists of a single-ended potential control unit, a low noise common gate difference-differential pair transimpedance amplifier and a low power VCO. The potentiostat current measuring unit can detect electrochemical current ranging from 500 nA to 7 μA from the VACNF working electrodes with high degree of linearity. This current corresponds to a range of glucose, which depends on the fiber forest density. The potentiostat consumes 71.7 μW of power from a 1.8 V supply and occupies 0.017 μm² of chip area realized in a 0.18 μm standard CMOS process.

Original language	English
Article number	7497511
Pages (from-to)	807-816
Number of pages	10
Journal	IEEE Transactions on Biomedical Circuits and Systems
Volume	10
Issue number	4
DOIs	https://doi.org/10.1109/TBCAS.2016.2557787
State	Published - Aug 2016

Keywords

Amperometry
glucose monitoring
potentiostat
transimpedance amplifier
vertically aligned carbon nanofibers

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10.1109/TBCAS.2016.2557787

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title = "A Glucose Biosensor Using CMOS Potentiostat and Vertically Aligned Carbon Nanofibers",

abstract = "This paper reports a linear, low power, and compact CMOS based potentiostat for vertically aligned carbon nanofibers (VACNF) based amperometric glucose sensors. The CMOS based potentiostat consists of a single-ended potential control unit, a low noise common gate difference-differential pair transimpedance amplifier and a low power VCO. The potentiostat current measuring unit can detect electrochemical current ranging from 500 nA to 7 μA from the VACNF working electrodes with high degree of linearity. This current corresponds to a range of glucose, which depends on the fiber forest density. The potentiostat consumes 71.7 μW of power from a 1.8 V supply and occupies 0.017 μm2 of chip area realized in a 0.18 μm standard CMOS process.",

keywords = "Amperometry, glucose monitoring, potentiostat, transimpedance amplifier, vertically aligned carbon nanofibers",

author = "\{Al Mamun\}, \{Khandaker A.\} and Islam, \{Syed K.\} and Hensley, \{Dale K.\} and Nicole McFarlane",

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AB - This paper reports a linear, low power, and compact CMOS based potentiostat for vertically aligned carbon nanofibers (VACNF) based amperometric glucose sensors. The CMOS based potentiostat consists of a single-ended potential control unit, a low noise common gate difference-differential pair transimpedance amplifier and a low power VCO. The potentiostat current measuring unit can detect electrochemical current ranging from 500 nA to 7 μA from the VACNF working electrodes with high degree of linearity. This current corresponds to a range of glucose, which depends on the fiber forest density. The potentiostat consumes 71.7 μW of power from a 1.8 V supply and occupies 0.017 μm2 of chip area realized in a 0.18 μm standard CMOS process.

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KW - transimpedance amplifier

KW - vertically aligned carbon nanofibers

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A Glucose Biosensor Using CMOS Potentiostat and Vertically Aligned Carbon Nanofibers

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