A convolutional neural network method for boundary optimization enables few-shot learning for biomedical image segmentation

Erica M. Rutter, John H. Lagergren, Kevin B. Flores

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

9 Scopus citations

Abstract

Obtaining large amounts of annotated biomedical data to train convolutional neural networks (CNNs) for image segmentation is expensive. We propose a method that requires only a few segmentation examples to accurately train a semi-automated segmentation algorithm. Our algorithm, a convolutional neural network method for boundary optimization (CoMBO), can be used to rapidly outline object boundaries using orders of magnitude less annotation than full segmentation masks, i.e., only a few pixels per image. We found that CoMBO is significantly more accurate than state-of-the-art machine learning methods such as Mask R-CNN. We also show how we can use CoMBO predictions, when CoMBO is trained on just 3 images, to rapidly create large amounts of accurate training data for Mask R-CNN. Our few-shot method is demonstrated on ISBI cell tracking challenge datasets.

Original languageEnglish
Title of host publicationDomain Adaptation and Representation Transfer and Medical Image Learning with Less Labels and Imperfect Data First MICCAI Workshop, DART 2019 and First International Workshop, MIL3ID 2019 Shenzhen, Held in Conjunction with MICCAI 2019 Shenzhen, 2019 Proceedings
EditorsQian Wang, Fausto Milletari, Nicola Rieke, Hien V. Nguyen, Badri Roysam, Shadi Albarqouni, M. Jorge Cardoso, Ziyue Xu, Konstantinos Kamnitsas, Vishal Patel, Steve Jiang, Kevin Zhou, Khoa Luu, Ngan Le
PublisherSpringer
Pages190-198
Number of pages9
ISBN (Print)9783030333904
DOIs
StatePublished - 2019
Externally publishedYes
Event1st MICCAI Workshop on Domain Adaptation and Representation Transfer, DART 2019, and the 1st International Workshop on Medical Image Learning with Less Labels and Imperfect Data, MIL3ID 2019, held in conjunction with 22nd International Conference on Medical Image Computing and Computer- Assisted Intervention, MICCAI 2019 - Shenzhen, China
Duration: Oct 13 2019Oct 17 2019

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11795 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference1st MICCAI Workshop on Domain Adaptation and Representation Transfer, DART 2019, and the 1st International Workshop on Medical Image Learning with Less Labels and Imperfect Data, MIL3ID 2019, held in conjunction with 22nd International Conference on Medical Image Computing and Computer- Assisted Intervention, MICCAI 2019
Country/TerritoryChina
CityShenzhen
Period10/13/1910/17/19

Keywords

  • Biomedical image segmentation
  • Convolutional neural network
  • Few shot learning

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